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  • Title: [In vitro enzyme inhibitory and in vivo cardioprotective activities of hibiscus (Hibiscus sabdariffa L.)].
    Author: Jonadet M, Bastide J, Bastide P, Boyer B, Carnat AP, Lamaison JL.
    Journal: J Pharm Belg; 1990; 45(2):120-4. PubMed ID: 2355305.
    Abstract:
    A crude hydroalcoholic extract from Hibiscus sabdariffa L. calyces showed in vitro an appreciable enzyme-inhibiting activity towards the Angiotensin I Converting Enzyme (ACE), attributable to flavones, but weak inhibiting activities towards elastase, trypsin and alpha-chymotrypsin. The angioprotective activity in vivo, also important, was due to flavones and anthocyanins.
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