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  • Title: Chronic rejection in single-lung transplantation manifested by obliterative bronchiolitis.
    Author: LoCicero J, Robinson PG, Fisher M.
    Journal: J Thorac Cardiovasc Surg; 1990 Jun; 99(6):1059-62. PubMed ID: 2359323.
    Abstract:
    Chronic rejection of the lung in patients with heart-lung transplants has most often been associated with the development of obliterative bronchiolitis. Previously only one patient receiving a single-lung transplant suffered from the development of this problem. We describe a patient whose obliterative bronchiolitis developed 9 months after single-lung transplantation. Progressive deterioration occurred until his death from obliterative bronchiolitis at 21 months after transplantation. The functional and histologic changes are described and the possible mechanisms discussed.
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