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  • Title: Matrix-assisted laser desorption ionization-time of flight mass spectrometry in clinical microbiology.
    Author: Patel R.
    Journal: Clin Infect Dis; 2013 Aug; 57(4):564-72. PubMed ID: 23595835.
    Abstract:
    Despite widespread application of nucleic acid diagnostics, cultures remain integral in modern laboratories. Because cultures detect a large number of organism types, it is unlikely that they will disappear from clinical practice in the near future. Their downside is slow turn-around time, impacted by time to growth and identification of that growth. The latter is expedited using a new proteomic technology, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).
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