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  • Title: [Treatment of ulcerative colitis by total colectomy ileal pouch-anal anastomosis].
    Author: Cui L.
    Journal: Zhonghua Wei Chang Wai Ke Za Zhi; 2012 Dec; 15(12):1221-3. PubMed ID: 23596667.
    Abstract:
    Ulcerative colitis (UC) is a relapsing and remitting disease characterised by chronic mucosal and submucosal inflammation of the colon and rectum. Treatment may vary depending upon the extent and severity of inflammation. Broadly speaking medical treatments can induce and maintain remission. Approximately 25% of patients with UC ultimately require colectomy for ineffective medical treatment or complications. Ileal pouch-anal anastomosis(IPAA) has become the standard of care for patients with ulcerative colitis who ultimately require colectomy.Improvement in pouch technique may decrease the perioperative complication rate and postoperative stool frequency. Laparoscopic IP AA can lessen surgical trauma,abdominal adhesion and intestinal obstruction. Timing of surgery, appropriate surgical technique , and prevention of postoperative complications are the keys to successful treatment of UC.
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