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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: The dysarthria-clumsy hand syndrome: a distinct clinical entity related to pontine infarction.
    Author: Glass JD, Levey AI, Rothstein JD.
    Journal: Ann Neurol; 1990 May; 27(5):487-94. PubMed ID: 2360789.
    Abstract:
    Using magnetic resonance imaging, we studied 6 patients with the dysarthria-clumsy hand syndrome. All were found to have pontine infarctions contralateral to the symptomatic side. Clinically, these patients exhibited dysarthria; "clumsiness," characterized by dysmetria, dysrhythmia, dysdiadochokinesia and sometimes truncal and gait ataxia; and mild ipsilateral weakness. Previous clinical-anatomical correlations for this syndrome are limited by inconsistencies in clinical diagnostic criteria and low-resolution imaging methods. In our patients, and in a review of the literature, the overwhelming majority of patients with the dysarthria-clumsy hand syndrome had pontine infarcts. We conclude that if rigid clinical criteria are used, the label of the dysarthria-clumsy hand syndrome predicts a lesion in the contralateral basis pontis.
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