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  • Title: Treatment of sickle cell leg ulcers with pentoxifylline.
    Author: Frost ML, Treadwell P.
    Journal: Int J Dermatol; 1990 Jun; 29(5):375-6. PubMed ID: 2361798.
    Abstract:
    A 58-year-old black man with leg ulcers of 43 years duration responded to pentoxifylline 400 mg tid in 8 months. The ability of pentoxifylline to increase erythrocyte flexibility and decrease blood viscosity was the basis for our use of this agent. Oral pentoxifylline may be a useful adjunct in healing sickle cell leg ulcers and preventing their recurrence.
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