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  • Title: NSAID single-drug-induced reactions.
    Author: Woessner KM, Castells M.
    Journal: Immunol Allergy Clin North Am; 2013 May; 33(2):237-49. PubMed ID: 23639711.
    Abstract:
    Nonsteroidal anti-inflammatory drugs (NSAIDs) are cyclooxygenase inhibitors with analgesic, anti-inflammatory, antipyretic, and antithrombotic effects. NSAIDs have been implicated in a variety of drug-induced reactions that are proved as or suspected of being mediated through a host immune response. Single-drug-induced reactions are the hallmark of these types of reactions. The types of single-drug-induced reactions are the confluence of 2 variables, the structure of the drug and the specific types of immune responses. This article identifies reactions patterns and the NSAIDs most likely to elicit each immune response.
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