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  • Title: Norepinephrine and serotonin increase the vasoconstrictor response of the perfused rat tail artery to changes in cytosolic Ca2+.
    Author: Thorin-Trescases N, Oster L, Atkinson J, Capdeville C.
    Journal: Eur J Pharmacol; 1990 Apr 25; 179(3):469-71. PubMed ID: 2364996.
    Abstract:
    Vasoconstriction and changes in cytosolic free Ca2+ concentrations (fura 2 with dual wavelength excitation) were measured simultaneously in the perfused tail artery of the rat. Vasoconstrictors (norepinephrine and 5-HT) appear to modulate contraction not only by changing the cytosolic free Ca2+ concentration but also by modifying the sensitivity of the contractile proteins to Ca2+.
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