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  • Title: [Relationships between serum ghrelin and lipid profile and serum leptin, adiponectin, and insulin among children in Beijing, China].
    Author: Du S, Hu X, Liu A, Zhang Q, Pan H, Ma G.
    Journal: Wei Sheng Yan Jiu; 2013 Mar; 42(2):252-6, 262. PubMed ID: 23654102.
    Abstract:
    OBJECTIVE: To study the relationship between serum ghrelin and lipid profile and serum leptin, adiponectin, and insulin among children in Beijing. METHODS: A total of 879 pupils aged 8 - 10 years were randomly selected. Height, body weight, waist circumference, body mass index (BMI), body fat percentage (%BF), blood lipid, serum leptin, insulin, adiponectin and ghrelin were measured in all samples. RESULTS: Ghrelin associated negatively with body weight, waist circumference, BMI, %BF, serum leptin level and positively with HDL-C. Factor analysis has shown five factors which were sufficient to explain correlations between variables-body composition and leptin, dyslipidemia, glucose metabolism and adiponectin. CONCLUSION: Serum ghrelin level correlated strongly with body weight, waist circumference, BMI, %BF and leptin, Our finding suggested significantly increased leptin levels following decreased ghrelin levels could mostly disordered adipose metabolism at early obesity in children.
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