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  • Title: [The diagnostic value of virus serology in patients with non-ischemic systolic heart failure and parvovirus B19 infection].
    Author: Nowalany-Kozielska E, Kozieł M, Domal-Kwiatkowska D, Dworniczak S, Wojnicz R, Wojciechowska C, Jachec W, Kawecki D, Smolik S, Weglarz L, Kozielski J.
    Journal: Wiad Lek; 2012; 65(4):211-5. PubMed ID: 23654140.
    Abstract:
    INTRODUCTION: We determined retrospective analysis of the diagnostic value of virus serology in patients with non-ischemic systolic heart failure and parvovirus B19 infection. MATERIAL AND METHODS: Virus serology and endomyocardial biopsy were performed in 31 patients with non-ischemic systolic heart failure hospitalized from 2001 to 2006 in our clinic. RESULTS: The serum specimens from 31 patients were tested for IgM and IgG antibody against parvovirus B19. IgM antibodies were identified in 3 patients and IgG antibodies were identified in 23 patients. All of the patients underwent endomyocardial biopsy which revealed chronic active myocarditis in 10 patients (32.4%), chronic persistent myocarditis in 14 patients (45.1%) and no myocarditis in 7 patients (22.5%). CONCLUSIONS: Virus serology has no relevance for the diagnosis of non-ischemic systolic heart failure caused by parvovirus B19 infection. The result of serological tests are positive more frequently than the biopsy specimens results.
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