These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Chlorhexidine release from orthodontic adhesives after topical chlorhexidine treatment.
    Author: Lim BS, Cheng Y, Lee SP, Ahn SJ.
    Journal: Eur J Oral Sci; 2013 Jun; 121(3 Pt 1):211-7. PubMed ID: 23659245.
    Abstract:
    This study was designed to investigate the ability of orthodontic adhesives to adsorb and release chlorhexidine (CHX) after periodic treatment with 1% CHX solution. Composite and resin-modified glass-ionomer cement (RM-GIC) adhesive disks were incubated with whole saliva or distilled water for 2 h. Release of CHX was measured using high-performance liquid chromatography after 1, 2, and 5 d of incubation, 1 min after exposure to 1% CHX solution. The CHX measurements were performed in a 5-d cycle, which was repeated four consecutive times (n = 7). The amount of CHX adsorbed and the cumulative amounts of CHX released, with respect to type of adhesive and saliva-coating, were analyzed using repeated-measures anova. Chlorhexidine-adsorbed orthodontic adhesives demonstrated a short-term release of CHX, which rapidly returned to near-baseline levels within 3 d. Saliva-coating did not significantly influence CHX release from RM-GIC, but increased the amount of CHX released from the composite. The amount of CHX released from the composite was 20-fold higher than that released from the RM-GIC after saliva-coating. The composite adhesive showed a greater adsorption capacity for CHX than did the RM-GIC, which was more evident after saliva-coating. This study suggests that composite adhesives may be a significantly more effective CHX reservoir than RM-GICs in the oral cavity filled with saliva.
    [Abstract] [Full Text] [Related] [New Search]