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  • Title: Five new flavonoid glycosides from Nervilia fordii.
    Author: Qiu L, Jiao Y, Xie JZ, Huang GK, Qiu SL, Miao JH, Yao XS.
    Journal: J Asian Nat Prod Res; 2013; 15(6):589-99. PubMed ID: 23659497.
    Abstract:
    Five new flavonoid glycosides, namely nervilifordins F-J (1-5), were isolated from the 60% EtOH extract of the aerial parts of Nervilia fordii, along with three first isolated flavonoids (7, 8, and 13) and five known flavonoids (6, 9-12). The structures of new compounds were elucidated on the basis of 1D and 2D NMR and MS studies. Their anti-inflammatory activities were tested by measuring their inhibitory effects on nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages. Compounds 2 and 5 showed interesting inhibition effects with their EC50 values of 15.15 μM and 14.80 μM, respectively.
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