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  • Title: Skeletal muscle pathology in AIDS: an autopsy study.
    Author: Wrzolek MA, Sher JH, Kozlowski PB, Rao C.
    Journal: Muscle Nerve; 1990 Jun; 13(6):508-15. PubMed ID: 2366823.
    Abstract:
    A survey of skeletal muscle pathology in 92 autopsied cases of AIDS revealed microscopic alterations in 64 cases. There were 40 cases of disuse atrophy, 8 of denervation atrophy, 2 of cryptococcal myositis, 1 of Mycobacterium avium intracellulare (MAI) infection and 2 of necrotizing myopathy associated with hyperkalemia. A second group of cases with changes of unknown etiology was found. These were tentatively ascribed to the direct or indirect action of HIV. This category includes 8 cases of inflammatory myopathy, 8 of necrotizing myopathy in absence of a known etiological factor, 3 of extreme atrophy and 4 of "regenerating" myopathy.
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