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  • Title: [Surfactant phospholipids in bronchoalveolar lavage fluid in smokers with healthy lungs and non-smokers].
    Author: Würtemberger G, Herceg R, Matthys H, Ferber E, Costabel U.
    Journal: Pneumologie; 1990 Feb; 44 Suppl 1():310-1. PubMed ID: 2367401.
    Abstract:
    The surfactant phospholipids were determined in the BA1 fluid of 9 smokers and 9 non-smokers with no disease of the lungs. The total phospholipid content was reduced significantly in smokers to 10 +/- 6 nmol/ml as compared with 24 +/- 10 nmol/ml in the non-smokers (p less than 0.02). The composition of major phospholipid fractions (phosphatidyl-choline and phosphatidyl-ethanolamine) did not differ between the two groups. Possible reasons for this reduction of surfactant in smokers are discussed.
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