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  • Title: [Fading of the provocation effect following inhaled provocation with carbachol].
    Author: Schlegel J, Schulz V.
    Journal: Pneumologie; 1990 Feb; 44 Suppl 1():355-7. PubMed ID: 2367416.
    Abstract:
    The results of the present study aimed at establishing the subsidence of the effect of inhalative provocation with carbachol show that no ceiling activity is reached. Rather, following a maximum effect that is achieved after approximately 2 minutes, spontaneous subsidence of the provocation-related changes occurs. The average duration of this subsidence to below the level of change that is considered significant for the respective measured parameter was between 20 and 25 minutes.
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