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  • Title: [Value of diagnostic procedures in fiberoptic bronchoscopy of pulmonary infections].
    Author: Mainz D, Mülleneisen N, Höffken G, Kemmerich B, Wagner J, Lode H.
    Journal: Pneumologie; 1990 Feb; 44 Suppl 1():471-2. PubMed ID: 2367438.
    Abstract:
    Fibreoptic bronchoscopy has become an important means of diagnosing infections of the lower respiratory tract, since it a method with few complications, whereas, on the other hand, the conventional non-invasive methods are hardly reliable in respect of diagnostic relevance. Frequent oropharyngeal contamination severely limits the significant assessment of the pathogenicity of cultured microorganisms. The protected specimen brush (PSB) or quantitative cultures of bronchoalveolar lavage (BAL) might be useful in solving this problem. These methods were studied in two prospective trials comprising 123 patients with suspected bronchopulmonary infection and 54 control patients. Both methods were found to be disappointing in respect of sensitivity; moreover, quantitative cultivation did not yield any differences with regard to specificity.
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