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  • Title: [IgG subclass distribution in the serum of patients with homozygous alpha1-antitrypsin deficiency].
    Author: Barth J, Winkler I, Schmidt EW, Braun BE, Möllmann HW, Skvaril F.
    Journal: Pneumologie; 1990 Feb; 44 Suppl 1():561-2. PubMed ID: 2367469.
    Abstract:
    In 12 patients with homozygotic ZZ-phenotype alpha 1 antitrypsin deficiency, the serum levels of the IgG subclasses IgG1-4 were studied. In four of these patients, isolated or combined disorders or defects in the distribution of the IgG subclasses were detected; in cases with low IgG2 and absent IgG3, the clinical course of the disease was complicated by bronchiectasis.
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