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  • Title: [Pulmonary gas exchange in conventional ventilation and high frequency ventilation in severe respiratory insufficiency].
    Author: Poller W, Machraoui A, Ulmer WT.
    Journal: Pneumologie; 1990 Feb; 44 Suppl 1():668-9. PubMed ID: 2367497.
    Abstract:
    During high frequency jet ventilation (HFJV) adequate alveolar ventilation may be achieved with lower (-35%, p less than 0.0005) central airway pressures than during conventional mechanical ventilation (CMV). Due to increasing ventilation-perfusion inequalities, however, intrapulmonary shunt is then considerably increased (+52%, p less than 0.0005). In disease states with extensive shunting (e.g. ARDS) both ventilation modes can provide sufficient oxygenation only if high PEEP is applied.
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