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  • Title: Association of L-tryptophan and an illness resembling eosinophilic fasciitis. Clinical and histopathologic findings in four patients with eosinophilia-myalgia syndrome.
    Author: Bulpitt KJ, Verity MA, Clements PJ, Paulus HE.
    Journal: Arthritis Rheum; 1990 Jul; 33(7):918-29. PubMed ID: 2369428.
    Abstract:
    The Centers for Disease Control has recently reported an association between the use of oral L-tryptophan preparations and a disease marked by severe myalgia, peripheral eosinophilia, and neuromuscular and cutaneous abnormalities. They have labeled the condition eosinophilia-myalgia syndrome. We report here the clinical and histopathologic findings in 4 patients who developed an illness resembling eosinophilic fasciitis following the initiation of oral L-tryptophan supplementation.
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