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  • Title: Three new ursane-type triterpenes from the leaves of Rehmannia glutinosa.
    Author: Zhang YL, Feng WS, Zheng XK, Cao YG, Lv YY, Chen H, Kuang HX.
    Journal: Fitoterapia; 2013 Sep; 89():15-9. PubMed ID: 23707195.
    Abstract:
    Three new ursane-type triterpenes, glutinosalactone A-C (1-3), were isolated from the 50% aqueous acetone extract of the leaves of Rehmannia glutinosa. Their structures were elucidated on the basis of spectral analysis (IR, NMR and MS spectroscopy). The cytotoxic effects of compounds 1-3 against three human cancer cell lines (MCF-7, MG63 and HepG2) were also evaluated. Compound 3 showed cytotoxic activities with IC50 values of 8.35-39.25 μM.
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