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  • Title: Cellular schwannoma masquerading as malignant peripheral nerve sheath tumour: a diagnostic dilemma.
    Author: Alam K, Jain A, Misra A, Khan AH.
    Journal: BMJ Case Rep; 2013 May 23; 2013():. PubMed ID: 23709140.
    Abstract:
    We present a case of a 15-year-old girl with a pulsatile, rapidly enlarging mass at the root of the nose suspected to be malignant. Excisional biopsy showed worrisome histological features; however, a final diagnosis of cellular schwannoma was reached excluding the possibility of malignant peripheral nerve sheath tumour by histological and immunohistochemical attributes. Cellular schwannoma, a pseudosarcomatous entity, is a rare benign neoplasm that may cause bone erosion and may be mistaken for a malignancy, clinically and histologically. Diagnosis of cellular schwannoma is essential to prevent mismanagement as it never metastasises and responds to local excision as opposed to aggressive treatment required by a malignant neoplasm.
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