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  • Title: Laser-activated adhesive films for sutureless median nerve anastomosis.
    Author: Barton M, Morley JW, Stoodley MA, Ng KS, Piller SC, Duong H, Mawad D, Mahns DA, Lauto A.
    Journal: J Biophotonics; 2013 Dec; 6(11-12):938-49. PubMed ID: 23712961.
    Abstract:
    A novel chitosan adhesive film that incorporates the dye 'Rose Bengal' (RB) was used in conjunction with a green laser to repair transected rat median nerves in vivo. Histology and electrophysiological recording assessed the impact of the laser-adhesive technique on nerves. One week post-operatively, the sham-control group (laser-adhesive technique applied on un-transected nerves) conserved the average number and size of myelinated fibres in comparison to its contralateral side and electrophysiological recordings demonstrated no significant difference with un-operated nerves. Twelve weeks after the laser-adhesive anastomoses, nerves were in continuity with regenerated axons that crossed the anastomotic site.
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