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  • Title: Chemical approach for interconversion of (S)- and (R)-α-amino acids.
    Author: Sorochinsky AE, Ueki H, Aceña JL, Ellis TK, Moriwaki H, Sato T, Soloshonok VA.
    Journal: Org Biomol Chem; 2013 Jul 21; 11(27):4503-7. PubMed ID: 23715058.
    Abstract:
    Here we report a general method for the preparation of unnatural (R)-α-amino acids via complexation of α-(phenyl)ethylamine derived chiral reagent (S)- with various (S)-α-amino acids. The reactions proceed with synthetically useful chemical yields and thermodynamically controlled diastereoselectivity. Chiral reagent (S)- can be conveniently recovered and reused without any loss of enantiomeric purity and reactivity.
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