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  • Title: Baboon syndrome induced by hydroxyzine.
    Author: Akkari H, Belhadjali H, Youssef M, Mokni S, Zili J.
    Journal: Indian J Dermatol; 2013 May; 58(3):244. PubMed ID: 23723506.
    Abstract:
    Hydroxyzine-induced drug eruptions are very rare. We report here a typical case of drug-related Baboon syndrome or symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) which was induced by hydroxyzine in a 60-year-old man. The diagnosis was confirmed by positive patch and oral accidental provocation tests with hydroxyzine. Patch tests and oral provocation tests with cetirizine and levocetirizine were negative. A review of the literature identified only 17 reported cases of hydroxyzine-induced drug eruptions. To the best of our knowledge, we report here the first case of hydroxyzine-induced SDRIFE.
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