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  • Title: High-density lipoprotein subfractions, apolipoproteins and antipyrine clearance in normal subjects.
    Author: Luoma PV, Rautio A, Stengård J, Sotaniemi EA, Marniemi J.
    Journal: Eur J Clin Pharmacol; 1990; 38(6):625-7. PubMed ID: 2373138.
    Abstract:
    Serum high density lipoprotein (HDL) subfractions HDL2 and HDL3, apolipoproteins, and plasma antipyrine clearance (AP-CL) rate, an index of liver microsomal enzyme activity, were determined in 21 healthy subjects. High HDL cholesterol and HDL2 cholesterol concentrations and HDL cholesterol/cholesterol and HDL2/HDL3 cholesterol ratios were associated with high AP-CL. Phenobarbital enhanced antipyrine elimination and increased the apolipoprotein A-I/A-II ratio. Subjects who had high AP-CL had a more antiatherogenic HDL subfraction and apolipoprotein profile than those with low AP-CL.
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