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  • Title: [Long-term maintenance therapy in duodenal ulcer. Efficacy and safety].
    Author: Penston J, Wormsley KG.
    Journal: Fortschr Med; 1990 May 10; 108(14):282-6. PubMed ID: 2373457.
    Abstract:
    The efficacy and safety of continuous (maintenance) treatment with ranitidine has been studied retrospectively in 388 patients with duodenal ulcer. The cumulative rate of symptomatic relapse was 16% after 5 years. Very few of the patients developed ulcer complications during maintenance treatment, with a cumulative risk of haemorrhage of 1.8% during 5 years. The patients developed no drug-related disease. We conclude that long-term, continuous treatment with ranitidine is effective in maintaining remission of duodenal ulcers, protects the patients against the risk of complications, and is safe.
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