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  • Title: Cutaneous leukocytoclastic vasculitis in the presence of methimazole therapy.
    Author: Ribeiro Cde O, Magrin PF, Vilar EA, Durães SM, Estrella RR.
    Journal: An Bras Dermatol; 2013; 88(2):283-6. PubMed ID: 23739718.
    Abstract:
    Treatment with antithyroid drugs may be accompanied by side effects. We present a patient diagnosed with Grave's Disease who developed extensive vasculitis in the lower limbs during methimazole use. After suspension of the methimazole and the introduction of prednisone in immunesupressor doses the cutaneous lesions started to involute. A terapêutica com drogas antitireoidianas pode ser acompanhada de efeitos colaterais. Apresentamos um caso de paciente com diagnóstico de Doença de Graves que na vigência da terapêutica com metimazol desenvolveu um quadro extenso de vasculite de membros inferiores. A partir da suspensão do metimazol e da introdução de prednisona em doses imunossupressoras as lesões cutâneas entraram em involução.
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