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Title: [X-chromosomal congenital retinoschisis. Clinical aspects and electrophysiology]. Author: Kellner U, Brümmer S, Foerster MH, Wessing A. Journal: Fortschr Ophthalmol; 1990; 87(3):264-8. PubMed ID: 2376375. Abstract: We evaluated retrospectively the clinical records and electrophysiological results of 52 patients suffering from X-linked congenital retinoschisis. Characteristic clinical findings were hyperopia (mean +2.3 +/- 3.1 D), reduced visual acuity (mean 0.24 +/- 0.2) and always macular pathology. Peripheral retinoschisis was present in 53% of the eyes. The natural course of the disease was normally stable. Complications were visual loss in 9.3%, vitreous hemorrhages in 4.7% and retinal detachments in 10.7% of the eyes. These complications generally occurred within the first decennium. Prophylactic laser coagulation was of no use because it was complicated by retinal detachment in 43% of our series. The electrooculogram was usually normal. In addition to the known electroretinographic findings of a low normal a-wave and reduced b-wave amplitudes, we found prolonged b-wave latencies and implicit times.[Abstract] [Full Text] [Related] [New Search]