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  • Title: Facile synthesis of benzofurans via copper-catalyzed aerobic oxidative cyclization of phenols and alkynes.
    Author: Zeng W, Wu W, Jiang H, Huang L, Sun Y, Chen Z, Li X.
    Journal: Chem Commun (Camb); 2013 Jul 28; 49(59):6611-3. PubMed ID: 23772445.
    Abstract:
    Regioselective synthesis of polysubstituted benzofurans using a copper catalyst and molecular oxygen from phenols and alkynes in a one-pot procedure has been reported. The transformation consists of a sequential nucleophilic addition of phenols to alkynes and oxidative cyclization. A wide variety of phenols and alkynes can be used in the same manner.
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