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  • Title: Tetrahydroquinolines and benzazepines through catalytic diastereoselective formal [4 + 2]-cycloaddition reactions between donor-acceptor cyclopropenes and imines.
    Author: Truong PM, Mandler MD, Zavalij PY, Doyle MP.
    Journal: Org Lett; 2013 Jul 05; 15(13):3278-81. PubMed ID: 23777207.
    Abstract:
    Regio- and diastereoselective Lewis acid catalyzed cycloaddition reactions between imines and donor-acceptor cyclopropenes generated from silyl-protected enoldiazoacetates provide direct access to stable cyclopropane-fused tetrahydroquinolines and, with cyclopropane ring opening under mild conditions, to 1H-benzazipine derivatives.
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