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  • Title: Macplocimine A, a new 18-membered macrolide isolated from the filamentous sulfur bacteria Thioploca sp.
    Author: Li X, Vanner S, Wang W, Li Y, Gallardo VA, Magarvey NA.
    Journal: J Antibiot (Tokyo); 2013 Jul; 66(7):443-6. PubMed ID: 23778115.
    Abstract:
    Macplocimine A (1), a rare naturally occurring 18-membered macrolide, was isolated from the marine-derived filamentous sulfur bacteria Thioploca sp. The structure was determined by a combination of spectroscopic techniques, including HRESIMS, 1D and 2D NMR analyses. 1 features a thymine group, which is attached to an aromatic fused 18-membered macrolide ring structure derived from a polyketide synthase biosynthetic pathway.
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