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  • Title: [The effect of tetracycline therapy on the laboratory indices of chlamydia infection in Reiter's disease (preliminary report)].
    Author: Khamraev AA, Pankratova VN, Brodinova NS, Orlova OE, Shubin SV.
    Journal: Revmatologiia (Mosk); 1990; (1):17-21. PubMed ID: 2377858.
    Abstract:
    The authors studied the effect of tetracycline therapy (short and long courses) on the indices of chlamydia infection (antigens and antibodies) in Reiter's urogenous disease. The concentration of tetracycline in the blood serum and synovial fluid when administered in a daily dose of 2.0 g (single dose 0.5 g) was determined. It has been established that tetracycline exerts an inhibitory effect on the chlamydia infection not in all the patients suffering from Reiter's disease despite sufficient concentration of the antibiotic in biological fluids (blood serum, synovial fluid). Prolonged courses of tetracycline therapy proved most effective.
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