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  • Title: [The results of the radiation treatment of cervical cancer using low, sensitizing doses of radiation].
    Author: Iakimova TP, Gerinshteĭn IG, Pashchenko NS, Lozinskaia IN, Kozyreva TV, Serebriakov AM.
    Journal: Vopr Onkol; 1990; 36(6):678-82. PubMed ID: 2378088.
    Abstract:
    Combined radiation treatment for cervical cancer is associated with radiation injury to the intestine, bladder, hemopoietic system and suppression of T-system, nonspecific immunity and thyroid function. Modified gamma-ray teletherapy was suggested which included low-dose (0.1 Gy) sensitizing irradiation of tumor and zones of regional dissemination prior to delivering therapeutic dose (1.9 Gy). The procedure assured lower incidence of radiation-induced reactions and complications, leukopenia and T-lymphocyte function suppression, stimulated nonspecific resistance and thyrotropic function of the pituitary, and provided normal function of the thyroid. As a result, five-year survival rate in patients with stage III cancer increased by 14%.
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