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  • Title: [Delta sleep-inducing peptide as a modulator of mediators acting on the heart].
    Author: Ul'ianinskiĭ LS, Zviaginstseva MA, Kosharskaia IL.
    Journal: Biull Eksp Biol Med; 1990 May; 109(5):419-20. PubMed ID: 2378944.
    Abstract:
    Experiments on 51 isolated rabbit hearts have documented, that delta sleep-inducing peptide (6 X 10(-6) M/l) has a modulating effect on the mediators influencing the heart. This peptide enhances negative chronotropic effect of acetylcholine (1 X 10(-6) M/l) and decreases positive chronotropic effect of noradrenaline (1 X 10(-6) M/l). Such effect may be one of mechanisms of changes in the extracardiac regulation on the heart influenced by this peptide.
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