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  • Title: The in vitro biosynthesis of dhurrin, the cyanogenic glycoside of Sorghum bicolor.
    Author: MacFarlane IJ, Lees EM, Conn EE.
    Journal: J Biol Chem; 1975 Jun 25; 250(12):4708-13. PubMed ID: 237909.
    Abstract:
    A microsomal fraction from seedlings of Sorghum bicolor (Linn) Moench has been shown to catalyze the conversion of L-tyrosine to p-hydroxymandelonitrile via p-hydroxyphenylacetaldoxime. This transformation is consistent with the general pathway for cyanogenic glycoside biosynthesis proposed on the basis of in vivo experiments. When the microsomal fraction was combined with a protein fraction from the soluble portion of the cell and uridine diphosphate glucose, it was possible to demonstrate the synthesis of the cyanogenic glycoside dhurrin from L-tyrosine.
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