These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Antiplasmodial and cytotoxic flavans and diarylpropanes from the stems of Combretum griffithii.
    Author: Moosophon P, Kanokmedhakul S, Kanokmedhakul K, Buayairaksa M, Noichan J, Poopasit K.
    Journal: J Nat Prod; 2013 Jul 26; 76(7):1298-302. PubMed ID: 23795891.
    Abstract:
    Four new flavans, griffinoids A-D (1-4), and two new diarylpropanes, griffithanes E and F (7 and 8), together with two known flavans (5 and 6), four known diarylpropanes, and β-sitosterol, were isolated from the EtOAc extract of the stems of Combretum griffithii. Compounds 3, 4, 5, and 9 exhibited weak antiplasmodial activity, with IC50 values of 15.74, 13.04, 9.66, and 14.45 μM, respectively. In addition, compounds 4, 5, and 8 also exhibited weak cytotoxicity toward one or more cancer cell lines including human epidermoid carcinoma, human breast cancer, and human small cell lung cancer cell lines.
    [Abstract] [Full Text] [Related] [New Search]