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  • Title: Cyclization-carbonylation-cyclization coupling reaction of α,β-alkynic hydrazones with palladium(II)-bisoxazoline catalyst.
    Author: Kusakabe T, Sagae H, Kato K.
    Journal: Org Biomol Chem; 2013 Aug 14; 11(30):4943-8. PubMed ID: 23804189.
    Abstract:
    A cyclization-carbonylation-cyclization coupling reaction (CCC-coupling reaction) of α,β-alkynic hydrazones, catalyzed by (box)Pd(II) complexes, afforded symmetrical ketones bearing two pyrazole groups in good to excellent yields. This method is applicable to a broad range of substrates.
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