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  • Title: Comparison of ocular biometry between eyes with chronic primary angle-closure glaucoma and their fellow eyes with primary angle-closure or primary angle-closure suspect.
    Author: Huang J, Wang Z, Wu Z, Li Z, Lai K, Ge J.
    Journal: J Glaucoma; 2015; 24(4):323-7. PubMed ID: 23807358.
    Abstract:
    PURPOSE: To compare the eye with chronic primary angle-closure glaucoma (CPACG) with its fellow eye without glaucoma damage and to determine the biometric differences that may predispose to development of CPACG. METHODS: Consecutive patients diagnosed with CPACG in 1 eye and primary angle-closure (PAC)/primary angle-closure suspected (PACS) in the fellow eye were recruited. The biometric parameters of both the eyes were measured by A-scan ultrasonic biometry and ultrasound biomicroscopy. Comparisons of visual function, baseline intraocular pressure (IOP), and the biometric measurements were made. RESULTS: Forty-one patients were recruited. Eyes with CPACG had worse visual function, higher baseline IOP, and larger cup-to-disc ratio than their fellow eyes with PAC/PACS (P<0.001). Eyes with CPACG had shallower anterior chamber depths, smaller anterior chamber angles, thinner irises, and longer iris-ciliary process distances than their fellow eyes with PAC/PACS (P<0.05). There were no significant differences in terms of lens thicknesses, axial lengths, lens vault, and trabecular-ciliary process distances. CONCLUSIONS: Lens thickness, lens location, and axial length do not appear to play a significant role in the progression from PAC/PACS to CPACG. A thin and anterior iris bowing may be related to the progression from PAC/PACS to CPACG.
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