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  • Title: Nepheliosyne B, a new polyacetylenic acid from the new caledonian marine sponge Niphates sp.
    Author: Legrave N, Hamrouni-Buonomo S, Dufies M, Guérineau V, Vacelet J, Auberger P, Amade P, Mehiri M.
    Journal: Mar Drugs; 2013 Jun 27; 11(7):2282-92. PubMed ID: 23807547.
    Abstract:
    A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.
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