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  • Title: Accuracy of prenatal culture in predicting intrapartum group B streptococcus colonization status.
    Author: Florindo C, Damião V, Lima J, Nogueira I, Rocha I, Caetano P, Ribeiro L, Viegas S, Gomes JP, Borrego MJ.
    Journal: J Matern Fetal Neonatal Med; 2014 Apr; 27(6):640-2. PubMed ID: 23808988.
    Abstract:
    OBJECTIVE: To evaluate the positive predictive value (PPV) of group B Streptococcus (GBS) cultures at 35-37 weeks of gestation relative to GBS colonization status at delivery. METHODS: Rectovaginal swabs from 221 women at labor in four Lisbon hospitals were collected for GBS screening according to the CDC guidelines. RESULTS: The PPV was 24.4%. IAP was administered to 100% of prenatally GBS positive women. There was no case of early onset GBS disease (EOD). CONCLUSIONS: Poor accuracy of prenatal cultures in identifying true candidates for IAP highlights the need for Portuguese clinical and laboratory guidelines to prevent EOD and antibiotic overtreatment of pregnant women.
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