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  • Title: Detection of benzoylecgonine (cocaine metabolite) in urine: a cost-effective low risk immunoassay procedure.
    Author: Moore FM, Simpson D.
    Journal: Med Lab Sci; 1990 Apr; 47(2):85-9. PubMed ID: 2381273.
    Abstract:
    Using Syva EMIT reagents and a Cobas-Bio centrifugal analyser we have developed a cost-effective assay for the detection in urine of benzoylecgonine, one of the main metabolites of cocaine. With this method up to 2470 samples can be assayed with a single 100-test EMIT Kit while maintaining acceptable precision. A mean CV of 7.0% was obtained for the concentration range 240-620 micrograms/l. Comparison of the method with the Abbott TDx system showed good correlation. The Cobas-Bio method is suitable for high-risk urines since heat treatment may be performed prior to analysis.
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