These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Biochemical effects of luxabendazole on Trichinella spiralis.
    Author: Criado-Fornelio A, de Armas-Serra C, Jimenez-Gonzalez A, Casado-Escribano N, Rodriguez-Caabeiro F.
    Journal: Parasitol Res; 1990; 76(6):518-20. PubMed ID: 2381894.
    Abstract:
    Biochemical changes produced by luxabendazole in muscle-stage Trichinella spiralis larvae consisted of a decrease in free glucose and glycogen levels (46.71% and 35.66%, respectively) after in vivo treatment, slight in vitro inhibition of fumarate reductase activity (24.15%) and, finally, inhibition of [3H]-colchicine-tubulin binding, which was found to be of a competitive nature, with an inhibition constant (Ki) of 0.9 x 10(-7) M. In a parallel study, luxabendazole did not appear to be inhibitory to [3H]-colchicine binding to pig-brain tubulin.
    [Abstract] [Full Text] [Related] [New Search]