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Title: Humoral immune responses in seals infected by phocine distemper virus. Author: Rima BK, Cosby SL, Duffy N, Lyons C, O'Loan D, Kennedy S, McCullough SJ, Smyth JA, McNeilly F. Journal: Res Vet Sci; 1990 Jul; 49(1):114-6. PubMed ID: 2382048. Abstract: Recently the isolation and characterisation of a morbillivirus which caused high mortality in common seals (Phoca vitulina) in 1988 have been reported. Because of the clinical and pathological similarity of the disease in seals to that of distemper in dogs, the name phocine distemper virus (PDV) has been proposed. There are marked differences in the virus-induced proteins of PDV compared to other morbilliviruses and the humoral immune response of moribund and dead seals to PDV was restricted to some of the internal antigens of PDV, similar to the response described earlier for canine distemper virus infection in dogs.[Abstract] [Full Text] [Related] [New Search]