These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Modification by alpha-interferon of ethanol-induced changes in the level of opioid peptides in the rat striatum and hypophysis].
    Author: Panchenko LF, Terebilina NN, Malinovskaia VV, Manakhova LS, Petrichenko OB, Balashov AM.
    Journal: Vopr Med Khim; 1990; 36(3):71-3. PubMed ID: 2382436.
    Abstract:
    Content of Met-enkephalin in striatum and of beta-endorphin in rat hypophysis were estimated after administration of ethanol and alpha-interferon into the animals. Ethanol decreased Met-enkephalin content in striatum and of beta-endorphin in hypophysis. Preadministration of alpha-interferon into brain ventricles before ethanol administration led to an increase in concentration of Met-enkephalin, while content of beta-endorphin was unaltered. In peripheric administration alpha-interferon normalized content of beta-endorphin in adenohypophysis but did not affect the Met-enkephalin concentration. Effects of alpha-interferon on content of Met-enkephalin and beta-endorphin, related to dissimilar organization of the opiate systems in hypophysis and striatum tissues, are discussed.
    [Abstract] [Full Text] [Related] [New Search]