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  • Title: High performance liquid chromatography methods for studying protein binding of aluminium in human serum in the absence and in the presence of desferrioxamine.
    Author: García Alonso JI, López García A, Pérez Parajón J, Blanco González E, Sanz Medel A, Cannata JB.
    Journal: Clin Chim Acta; 1990 Jul; 189(1):69-79. PubMed ID: 2383920.
    Abstract:
    Ion-exchange high performance liquid chromatography of serum proteins was combined with aluminium determination by electrothermal-atomisation-atomic-absorption spectroscopy and fluorimetry for studying the distribution of aluminium in human serum in the absence and in the presence of desferrioxamine. Aluminium was eluted as a single peak in the same fraction as transferrin. However, following the addition of desferrioxamine most of the aluminium was liberated from transferrin and become attached to the chelator.
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