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  • Title: Umbilical artery serum chitotriosidase concentration in pregnancies complicated by preeclampsia and relationship between chitotriosidase levels and fetal blood flow velocity.
    Author: Aksoy Ü, Aksoy H, Açmaz G, Babayiğit M, Kandemir Ö.
    Journal: Hypertens Pregnancy; 2013 Nov; 32(4):401-9. PubMed ID: 23844836.
    Abstract:
    OBJECTIVE: To evaluate the significance of umbilical cord chitotriosidase concentrations in pregnancies with mild preeclampsia and explore the relationship between fetal chitotriosidase levels and fetal blood flow velocity. METHOD: The study population included control group (n=40) and study group with mild preeclampsia (n=40). Umbilical cord blood samples were collected immediately after delivery. Umbilical artery (UA) flow velocity waveform was determined just before delivery. RESULTS: Umbilical cord chitotriosidase levels and UA S/D rate were significantly high in preeclamptic group. CONCLUSION: Chitotriosidase may be useful biochemical marker of fetal compromise that reflects the severity of fetoplacental blood flow resistance in pregnancies complicated by preeclampsia.
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