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  • Title: Topical Mitomycin C application for esophageal stricture: safe, precise, and novel endoscopic technique.
    Author: El-Asmar KM.
    Journal: J Pediatr Surg; 2013 Jun; 48(6):1454-7. PubMed ID: 23845649.
    Abstract:
    PURPOSE: The first line of management of benign esophageal stricture is endoscopic dilatation; however, multiple sessions are usually indicated especially in resistant cases. Topical Mitomycin C (MCC) application is a new adjuvant treatment in the management of esophageal stricture with promising results in different case series. Several techniques have been reported for application; nevertheless, the ideal technique has not been described yet. MATERIAL AND METHODS: In this series we have devised a new technique using both the flexible and the rigid endoscope and a specially designed Nelaton catheter. RESULTS: This technique was applied in 38 sessions for 16 caustic esophageal strictures with technical success in all cases. No procedure-related complications were observed in this series. CONCLUSION: This novel technique is feasible and effective and can be considered as standard for topical MMC application on esophageal stricture.
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