These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of electrical discharging on formation of nanoporous biocompatible layer on Ti-6Al-4V alloys.
    Author: Yang TS, Huang MS, Wang MS, Lin MH, Tsai MY, Wang PY.
    Journal: Implant Dent; 2013 Aug; 22(4):374-9. PubMed ID: 23846526.
    Abstract:
    PURPOSE: In this study, the electrical discharge machining (EDM) was formed on the surface of the Ti-6Al-4V (Ti64) specimen. MATERIALS: The properties of adhesion and proliferation of MG-63 cells were evaluated the interactions between the EDM-treated layer and cells. RESULTS: The incorporation of oxygen roughened the EDM-treated specimen surface on a microscale, where the nanoscale pores were superimposed. The EDM-treated layer, which can generate the thick anatase TiO2 on the Ti64 surface, afforded a cytocompatible environment. In cell culture, alkaline phosphatase activity and osteocalcin can be dramatically enhanced on the EDM-treated surfaces when compared with the untreated surface. In addition, the increase in peak currents to the EDM functionalization led to enhancement of multiple osteoblast functions. CONCLUSIONS: This study reveals that the chemistry and crystallinity of the EDM-treated layer played important roles in affecting osteoblastic responses to the specimens, which provided insight into the development of new biomedical implant surfaces.
    [Abstract] [Full Text] [Related] [New Search]