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Title: Detection of single-nucleotide variations by monitoring the blinking of fluorescence induced by charge transfer in DNA. Author: Kawai K, Majima T, Maruyama A. Journal: Chembiochem; 2013 Aug 19; 14(12):1430-3. PubMed ID: 23846860. Abstract: Charge transfer dynamics in DNA: Photo-induced charge separation and charge-recombination dynamics in DNA was assessed by monitoring the blinking of fluorescence. Single nucleotide variations, mismatch and one base deletion, were differentiated based on the length of the off-time of the blinking, which corresponds to the lifetime of the charge-separated state.[Abstract] [Full Text] [Related] [New Search]