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  • Title: Evaluation of salivary sialic acid levels in acute lymphoblastic leukemic children and its correlation with dental caries experience.
    Author: Joshi S, Hegde AM, Rai K, Shetty S.
    Journal: J Clin Pediatr Dent; 2013; 37(3):309-13. PubMed ID: 23855178.
    Abstract:
    AIM: The aim of present study was to evaluate the salivary sialic acid levels in Acute Lymphoblastic Leukemic (ALL) children and to correlate it with dental caries experience. METHOD: A total of 120 children aged 4-10 yrs were divided into 4 groups of 30 each. Dental caries experience was recorded followed by un-stimulated saliva collection. RESULTS: The mean salivary sialic acid levels of the study group were much higher when compared with the control group, which was statistically significant. A linear relationship between salivary sialic acid levels and dental caries in leukemic children was observed. CONCLUSION: The findings of our study conclude that salivary sialic acid levels may have a potent activity in dental caries process and can be used as a useful marker in cancer
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